- U.K.
- U2
- UB40
- U.D.O.
- UFO
- UGK
- Ugly Stick
- Dave Uhrich
- Ulfur
- James Blood Ulmer
- Ultimate Fakebook
- The Ultra Violets
- Ultravox
- Pete Um
- Umphrey's McGee
- Uncle Art
- Uncle Green / 3 Lb. Thrill
- Uncle Lucius
- Uncle Tupelo
- The Uncluded
- Under The Influence Of Giants
- Under The Sun
- Carrie Underwood
- Uniform Motion
- Union
- Unitopia
- Unknown Instructors
- Unlettered
- Upchuck
- The Upper Crust
- Uriah Heep
- Us3
- Usher
- George Usher
- Utopia